Paula Wrinkle Shot Serum Duo

Paula Wrinkle Shot Medical Serum Duo

[Set Contents]

• Agent A (glass vial) 1.5 mL × 2

• Agent B (tube) 13.5 mL × 2

• Nozzle

• Main cap × 2

To be used as a pre-treatment: after cleansing, before lotion.

Sales Name: POLA Wrinkle Shot Medical Serum Duo

Deliver *NEI-L1®*¹ everywhere.
A wrinkle-improving pre-treatment² serum containing the active ingredient NEI-L1.
Its fresh, smooth texture spreads evenly across the entire face and absorbs quickly.
Because NEI-L1¹ is delicate and gradually decomposes when in contact with water, POLA has developed Japan’s first³ wrinkle-improving quasi-drug serum that requires self-mixing of two agents to deliver it effectively across the entire face.

¹ Sodium 3-isopropyl-oxopropylaminocarbonyl-pyrrolidinylcarbonyl-methyl-propylaminocarbonyl-benzoylaminoacetate trifluoride
² Used after cleansing, before lotion
³ First approved in March 2024 as a dual-agent wrinkle-improving quasi-drug

• Quasi-drug

• Allergy tested (does not guarantee allergy-free for all users)

For scattered wrinkles across the entire face

POLA newly focused on the fact that neutrophil elastase, one of the causes of wrinkles, is present in various areas of the face.
Skin free from scattered wrinkles appears brighter and firmer.
By combining two agents yourself, POLA’s original Wrinkle Shot Mix Formula allows the wrinkle-improving active ingredient NEI-L1¹ to be used in a fresh, spreadable texture for the entire face.
Aims to improve wrinkles, achieving smooth, hydrated, plump, and radiant skin.

What are scattered wrinkles?
Wrinkles in the dermis that appear in various parts of the face.

• They can be hard to notice as they appear in places you don’t consciously recognize.

• They remain visible even when expressionless.

• They often form in areas with mild, continuous expression pressure.

Theory

With a dynamic approach, POLA focused on the presence of neutrophil elastase across the whole face.
Proposes the “Smoothing Dynamism Theory”, which aims to improve wrinkles with a texture that can be applied evenly over the entire face.

Ingredients

Formulated with wrinkle-improving active ingredients and three original POLA moisturizing complexes:

• POLA’s original wrinkle-improving active ingredient *NEI-L1®*¹

• POLA’s original moisturizing complex Neernergy²

• POLA’s original moisturizing complex D-Liquid³

• POLA’s original moisturizing complex NERE Liquid N⁴

¹ Sodium 3-isopropyl-oxopropylaminocarbonyl-pyrrolidinylcarbonyl-methyl-propylaminocarbonyl-benzoylaminoacetate trifluoride
² Birch extract + eucalyptus extract
³ Koki extract-2 + linden extract
⁴ Oil-soluble peach leaf extract + horsetail extract

Fresh, all-over texture

A moist-fresh texture that spreads smoothly across the entire face and absorbs quickly.
Each use leaves skin feeling smoother and softer.

Product Features

Formula (1): Wrinkle Shot Mix Formula

• A dual-agent mixing system designed to deliver NEI-L1 across the whole face with a fresh, spreadable texture.

Formula (2): Firmness Veil Design

• Forms a taut veil of firmness for smooth, refined results.

• Additionally contains Moist Catcher.

¹ Sodium 3-isopropyl-oxopropylaminocarbonyl-pyrrolidinylcarbonyl-methyl-propylaminocarbonyl-benzoylaminoacetate trifluoride
² Polyglyceryl-3 methylglucose distearate (moisturizer)
³ Verified using artificial leather modeled after skin, compared with untreated samples

Commitment to Society & Environment

• Outer box: printed with bio-based ink

• Outer box: uses FSC-certified paper

• Container: made with recyclable transparent glass

• Container: uses eco-friendly bio-PE

• Pamphlet: web-based leaflet adopted

How to Use

Use Wrinkle Shot Medical Serum Duo before all-in-one skincare items.
If using an all-in-one product, apply Wrinkle Shot Geo Serum Protian and Wrinkle Shot Medical Serum afterwards.

Preparation before use
Do not use Agents A or B separately without mixing.

1. Remove the cap from Agent A. The vial already contains 1.5 mL of Agent A.

2. Twist off the cap of Agent B. Hold the tube gently to prevent splattering.

3. Attach Agent B to the opening of Agent A’s vial and squeeze the entire contents of Agent B into it. Ensure all contents are transferred. Keep the vial upright.

4. Replace the cap removed in step 1, then shake the vial vigorously more than 10 times.

5. Remove the cap again, attach the provided nozzle and main cap. Discard the original cap.

6. Finally, write the mixing date on the designated space of the Agent A vial with a permanent marker. If it fades, trace over or rewrite it.

Once mixed, use within one month. Do not use after two months.

Recommended Usage & Method

• Use after face wash or massage.

• Remove the main cap, turn the container upside down, and dispense an appropriate amount (approx. 1.5 cm diameter for the whole face) into your hand. Apply gently across the face.

• Follow with lotion.