{"product_id":"pola-wrinkle-shot-medical-serum-duo-single-set-15ml","title":"Pola Wrinkle Shot Medical Serum Duo Single Set 15mL","description":"\u003cdiv style=\"font-family: Arial, sans-serif; line-height: 1.6;\"\u003e\n\u003ch3 class=\"tw-data-text tw-text-large tw-ta\" dir=\"ltr\" data-placeholder=\"Translation\"\u003eAbout Product\u003c\/h3\u003e\n\u003ch1\u003e\u003cspan\u003ePOLA Wrinkle Shot Medical Serum Duo – Single Set (15mL)\u003c\/span\u003e\u003c\/h1\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eJapanese Anti-Wrinkle Serum | Full-Face Wrinkle Care | NEI-L1® | Two-Part Mixing Formula\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eDiscover a new approach to full-face wrinkle care with \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003ePOLA Wrinkle Shot Medical Serum Duo\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, an innovative Japanese anti-wrinkle serum featuring POLA's proprietary active ingredient \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eNEI-L1®\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eUnlike conventional wrinkle serums, Medical Serum Duo uses a unique \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003etwo-part formula that is mixed before use\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e. This technology allows POLA to incorporate its delicate wrinkle-improving ingredient into a fresh, lightweight serum that spreads comfortably across the entire face.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eDesigned to address wrinkles appearing in different areas of the face, the serum combines clinically recognised Japanese quasi-drug wrinkle care with moisturising ingredients for smoother, firmer and more radiant-looking skin.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eWhat's Included?\u003c\/span\u003e\u003c\/h2\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003e\u003cspan\u003eComponent\u003c\/span\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cspan\u003eQuantity\u003c\/span\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eFormula A – Glass Bottle\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e1.5mL × 1\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eFormula B – Tube\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e13.5mL × 1\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eNozzle and Main Cap\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e1 Set\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e\u003cspan\u003eTotal Serum Volume\u003c\/span\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e\u003cspan\u003e15mL\u003c\/span\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eImportant:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e The two formulas must be mixed before use. This is a single-set product containing one complete 15mL serum preparation.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eKey Benefits\u003c\/span\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eApproved wrinkle improvement:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Contains POLA's proprietary active ingredient NEI-L1®, approved in Japan for improving wrinkles.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFull-face application:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Designed to spread easily over the entire face rather than only individual wrinkle-prone areas.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eInnovative two-part formula:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Separates the ingredients until mixing to accommodate the water-sensitive properties of NEI-L1®.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFresh, lightweight texture:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Glides smoothly across the skin and absorbs quickly.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFirming-feel veil:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Creates a smooth, supple finish with a feeling of firmness.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMoisturising care:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Features three POLA-exclusive moisturising complexes and Moist Catcher.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSmooth, radiant appearance:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Helps skin feel hydrated and look firmer, smoother and more luminous.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003e\u003cspan\u003eWhat Makes POLA Wrinkle Shot Medical Serum Duo Different?\u003c\/span\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cspan\u003e1. NEI-L1® – POLA's Proprietary Wrinkle-Improving Ingredient\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eAt the heart of Medical Serum Duo is \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eNEI-L1®\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, an active ingredient independently developed by POLA for wrinkle improvement.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003ePOLA's wrinkle research focuses on \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eneutrophil elastase\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, an enzyme associated with wrinkle formation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eBuilding on its research, POLA identified the presence of neutrophil elastase across various facial areas and developed Medical Serum Duo to support a more comprehensive approach to wrinkle care.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe serum is classified as a \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eJapanese quasi-drug\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, with NEI-L1® as its approved wrinkle-improving active ingredient.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003e2. Full-Face Care for Scattered Wrinkles\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003ePOLA introduces the concept of \u003c\/span\u003e\u003cem\u003e\u003cspan\u003escattered wrinkles\u003c\/span\u003e\u003c\/em\u003e\u003cspan\u003e—dermal wrinkles that appear across different areas of the face.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThese wrinkles may:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eDevelop in areas that are not immediately noticeable.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eRemain visible even when the face is relaxed.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eOccur in areas exposed to relatively gentle facial-expression pressure.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eRather than concentrating exclusively on individual lines, Medical Serum Duo is designed for convenient application across the entire face.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIts fluid consistency makes it easier to incorporate wrinkle care into a daily skincare routine.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003e3. Wrinkle Shot Mix Formula – Innovative Two-Part Technology\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eNEI-L1® is a delicate ingredient that gradually breaks down when exposed to water.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eTo create a fresh, water-rich texture suitable for full-face use, POLA developed its proprietary \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eWrinkle Shot Mix Formula\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe product contains two separate preparations:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormula A – 1.5mL\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eSupplied in a glass bottle.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFormula B – 13.5mL\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eSupplied in a tube.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe two preparations are mixed by the user before application, creating the finished serum.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003ePOLA states that the two-part mixing format received its first Japanese approval as a wrinkle-improving quasi-drug in \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eMarch 2024\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThis innovative system makes it possible to enjoy NEI-L1® in a lightweight serum texture designed for full-face application.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003e4. Moist Fresh Texture – Lightweight, Smooth and Comfortable\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eMedical Serum Duo features a \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eMoist Fresh Texture\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e that combines a refreshing feel with a soft, smooth finish.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe serum:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eSpreads easily across the entire face.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eBlends quickly into the skin.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eFeels fresh and comfortably moisturising.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eLeaves skin feeling smooth and supple.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eSupports a firmer, more radiant-looking complexion.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eIts lightweight consistency makes it particularly suitable for those who prefer full-face wrinkle care without a heavy cream texture.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003e5. Firming Veil and Moist Catcher Technology\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003ePOLA designed the formula to create a delicate veil over the skin, helping deliver a smooth finish with a feeling of firmness.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe serum also contains \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eMoist Catcher\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, a moisturising ingredient that supports the skin's hydration.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMoist Catcher Ingredient:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Polyglyceryl-3 Methylglucose Distearate\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eTogether, these features help create a comfortable, moisturised and smooth skin feel.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eFeatured Ingredients\u003c\/span\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cspan\u003eNEI-L1® – Active Wrinkle-Improving Ingredient\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003ePOLA's proprietary ingredient approved in Japan for wrinkle improvement.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFull Ingredient Name:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Sodium Trifluoroisopropyl Oxopropylaminocarbonyl Pyrrolidinecarbonyl Methylpropylaminocarbonyl Benzoylaminoacetate.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eNi-Renergy – POLA Original Moisturising Complex\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eA proprietary moisturising combination of:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eBirch Extract\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eEucalyptus Extract\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003eD Liquid – POLA Original Moisturising Complex\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eA proprietary moisturising combination of:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eKouki Extract-2\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eLinden Extract\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003eNERE Liquid N – POLA Original Moisturising Complex\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eA proprietary moisturising combination of:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eOil-Soluble Peach Leaf Extract\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eHorsetail Extract\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003eMoist Catcher\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003ePolyglyceryl-3 Methylglucose Distearate\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eA moisturising ingredient incorporated into the serum's formulation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThese ingredients complement the wrinkle-improving active ingredient by supporting hydration and a supple skin feel.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eHow to Use POLA Wrinkle Shot Medical Serum Duo\u003c\/span\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cspan\u003eStep 1 – Mix the Two Formulas\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eBefore the first application, combine \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eFormula A (1.5mL)\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e and \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eFormula B (13.5mL)\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e according to POLA's official mixing instructions.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eAttach the supplied nozzle and cap as directed.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eImportant:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Follow the product's official instructions for the exact mixing procedure, handling and use period after mixing.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eStep 2 – Apply After Cleansing\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eMedical Serum Duo is a \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003epre-lotion serum\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eUse it after washing your face and \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003ebefore applying facial lotion or toner\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eStep 3 – Apply Across the Entire Face\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eSpread the prepared serum gently and evenly across the face.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIts lightweight, moisturising texture is designed to blend quickly and comfortably into the skin.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eStep 4 – Continue Your Skincare Routine\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eFollow with your usual facial lotion and other skincare products.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eFor detailed mixing instructions and the complete ingredient list, scan the \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eQR code printed on the product's outer packaging\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e to access POLA's official digital leaflet.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eMedical Serum Duo vs Medical Serum N\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eBoth products belong to POLA's Wrinkle Shot range and feature the proprietary active ingredient NEI-L1®, but their formats and intended application styles differ.\u003c\/span\u003e\u003c\/p\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003e\u003cspan\u003eFeature\u003c\/span\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cspan\u003eMedical Serum Duo\u003c\/span\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cspan\u003eMedical Serum N\u003c\/span\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003ePrimary Focus\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eFull-face wrinkle care\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eTargeted wrinkle care\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eActive Ingredient\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eNEI-L1®\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eNEI-L1®\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eTexture\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eFresh, lightweight serum\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eTargeted serum formula\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003ePreparation\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eMix two formulas before use\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eReady to use\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eApplication Timing\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eAfter cleansing, before lotion\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eFollow product directions\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003eFormat\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eTwo-part mixing system\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eSingle ready-to-use product\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eChoose Medical Serum Duo\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e if you want to incorporate NEI-L1® into a lightweight, full-face skincare routine.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eChoose Medical Serum N\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e if you prefer a ready-to-use product for targeted wrinkle care.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eConsideration for Skin Sensitivity\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003ePOLA states that Medical Serum Duo has been \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eallergy tested\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eHowever, this does not guarantee that allergic reactions will not occur in every individual.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIf you have particularly sensitive skin or a history of reactions to skincare ingredients, review the complete ingredient list before use.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eSustainability and Packaging\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003ePOLA has incorporated several environmentally conscious elements into Medical Serum Duo's packaging:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBio-based ink\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e used for the outer carton.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eForest-certified paper\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e used for the outer carton.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eRenewable transparent glass\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e used for the container.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eBio-based polyethylene (Bio-PE)\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e used in the packaging.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eDigital product leaflet\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e accessible via the QR code on the outer carton.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eThese choices reflect POLA's efforts to reduce the environmental impact of its product packaging.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan\u003eProduct Details\u003c\/span\u003e\u003c\/h2\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003e\u003cspan\u003eSpecification\u003c\/span\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cspan\u003eDetails\u003c\/span\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e\u003cspan\u003eBrand\u003c\/span\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003ePOLA\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e\u003cspan\u003eProduct Name\u003c\/span\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eWrinkle Shot Medical Serum Duo – Single Set\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e\u003cspan\u003eJapanese Name\u003c\/span\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eリンクルショット メディカル セラム デュオ 1本セット\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e\u003cspan\u003eCategory\u003c\/span\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eAnti-Wrinkle Facial Serum\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e\u003cspan\u003eTotal Volume\u003c\/span\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e15mL\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e\u003cspan\u003eFormula A\u003c\/span\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e1.5mL × 1\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e\u003cspan\u003eFormula B\u003c\/span\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e13.5mL × 1\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e\u003cspan\u003eAccessories\u003c\/span\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eNozzle and Main Cap\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e\u003cspan\u003eActive Ingredient\u003c\/span\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eNEI-L1®\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e\u003cspan\u003eApplication Area\u003c\/span\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eEntire Face\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e\u003cspan\u003eApplication Timing\u003c\/span\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eAfter Cleansing, Before Lotion\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e\u003cspan\u003eFormula Type\u003c\/span\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eTwo-Part Mixing Serum\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e\u003cspan\u003eJapanese Classification\u003c\/span\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eQuasi-Drug\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e\u003cspan\u003eAllergy Tested\u003c\/span\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eYes; individual reactions may still occur\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e\u003cspan\u003eInstructions\u003c\/span\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eDigital Leaflet via Packaging QR Code\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003e\u003cspan\u003eFrequently Asked Questions\u003c\/span\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cspan\u003eWhat is POLA Wrinkle Shot Medical Serum Duo?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eIt is a Japanese anti-wrinkle facial serum featuring POLA's proprietary active ingredient NEI-L1®. The product uses a two-part mixing formula to create a lightweight serum designed for full-face application.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eWhat is the difference between Medical Serum Duo and Medical Serum N?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eMedical Serum Duo is designed for full-face use and requires mixing two formulas before application. Medical Serum N is a ready-to-use product intended for more targeted wrinkle care. Both contain NEI-L1®.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eWhy does Medical Serum Duo need to be mixed?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eNEI-L1® gradually breaks down when exposed to water. POLA developed the two-part Wrinkle Shot Mix Formula to accommodate this ingredient while creating a fresh, lightweight texture suitable for the entire face.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eDoes POLA Wrinkle Shot Medical Serum Duo improve wrinkles?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eYes. The serum contains NEI-L1®, an active ingredient approved in Japan for wrinkle improvement. Results vary between individuals.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eCan I use Medical Serum Duo on my entire face?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eYes. Medical Serum Duo is specifically formulated to spread comfortably across the entire face.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eShould I use Medical Serum Duo before or after toner?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eUse Medical Serum Duo \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eafter cleansing and before facial lotion or toner\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eHow much product is included in the single set?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eThe set contains \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003e15mL in total\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, consisting of Formula A (1.5mL) and Formula B (13.5mL), plus a nozzle and cap.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eIs Medical Serum Duo suitable for sensitive skin?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eThe product has been allergy tested, but this does not guarantee that every user will be free from allergic reactions.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eWhere can I find the mixing instructions?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003ePOLA provides a digital product leaflet. Scan the QR code on the outer carton to access detailed mixing instructions, product information and the full ingredient list.\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv id=\"tw-container\" class=\"\" data-cp=\"1\" data-ddp=\"true\" data-drd=\"1700\" data-drt=\"10000\" data-is-rde=\"false\" data-is-ver=\"false\" data-nnttsvi=\"1\" data-sm=\"1\" data-ssbp=\"false\" data-sugg-time=\"500\" data-sugg-url=\"https:\/\/clients1.google.com\/complete\/search\" data-tcp=\"geluk met jou verjaarsdag,gelukkige verjaarsdag,awoda pa,???????????? ?????????,?????? ?????????? ????????,???????????????????????? ????????? ??????????????????,aski mara phuqhawi,do??um g??n??n m??bar??k,ad g??n??n m??bar??k,?? ???????? ?????€??????????????,???????????? ?€?????????? ??????,???????????? ????????? ?????? ????????? ???????????????,sanb?? sanb??,????????? ?????????????????????,sretan ro??endan,per molts anys,feli?? aniversari,malipayong adlawng natawhan,???????? ???????????? ?????????? ?????????? ??????,felice anniversariu,v??echno nejlep???? k narozenin??m,pen-blwydd hapus,penblwydd hapus,tillykke med f??dselsdagen,alles gute zum geburtstag,???????????????????????? ???????????????,???????????????? ?????????????????????€??????,dzigbe z?? nyuie na w??,?????????????????? ????????????????,happy birthday,feli??an naski??tagon,feliz cumplea??os,palju ??nne s??nnip??evaks,zorionak,?????????? ??????????,hyv???? syntym??p??iv????,joyeux anniversaire,lokkige jierdei,l?? breithe sona,l?? breithe shona duit,co-l??-breith math,feliz aniversario,vy'apav???,?????????????????????????????€ ???????????€,?????????????????????????????€ ????????????????????????,???????????????????????? ?????€ ????????????????????????,barka da ranar haihuwa,hau??oli l?? h??nau,????????????????????? ?????€ ??????????????????????????????,????????????????????? ?????€ ??????????????????????????????,sretan ro??endan,b??n f??t,boldog sz??let??snapot,?????????????? ???????€?????????€,selamat ulang tahun,ezi ncheta ???b???ch??? ???m???m???,ezi ncheta ???m???m???,naragsak a panagkasangay,til hamingju me?? afm??li??,buon compleanno,?????? ?????????? ??????,????????????????????????,???????????????????????????,sugeng ambal warsa,sugeng tanggap warsa,???????????????????????? ??????????????????????????? ????????????,????????????????????? ??????????????????????????? ????????????,?????????? ?????? ?????????? ????????????,?????????????? ????????????????,????????€????????????????????????????????€????????????,????????€??????????€??????????????€???€????????????,????????????????????????????????? ???????????????????????????,???????????????????????? ???????????????????????????,?????? ???????????????,?????? ????????????,api batde,rojb??na te p??roz be,?????????????? ?????????????? ??????????,?????????????? ?????????????? ?????????? ????????????????????,felix natalis,alles guddes fir de gebuertsdag,amazaalibwa amalungi,mbotama elamu,?????????????????????????????€?????????,??????????€???????????€???????????€???€?????????,su gimtadieniu,piancham chibai,daudz laimes dzim??anas dien??,???????????????????????? 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?????? ??????????,?? ???????? ?????€??????????????,???????????? ??????????,???????????? ?????????? ????,tug??ilgan kuningiz bilan,tug'ilgan kun muborak bo'lsin,ch??c m???ng sinh nh???t,mini emnandi,nwabela usuku lwakho owaqala ngalo,o ku?? a?€ya??j????? ???j????? i?€bi??,o ku ojo ibi,????????????,????????????,sikufisela usuku lokuzalwa oluhle,usuku olumnandi lokuzalwa\" data-uilc=\"en\" data-vil=\",af,af-ZA,am,am-ET,ar-EG,ar-AE,ar-KW,ar-QA,ar,ar-IL,ar-JO,ar-LB,ar-PS,az,az-AZ,bg,bg-BG,bn,bn-BD,bn-IN,ca,ca-es,cs,cs-CZ,de,de-DE,de-CH,de-AT,de-LI,en,en-US,en-CA,en-AU,en-NZ,en-GB,en-IN,en-KE,en-TZ,en-NG,en-GH,en-PH,en-ZA,es,es-ES,es-AR,es-UY,es-419,es-BO,es-CL,es-CR,es-CO,es-DO,es-EC,es-GT,es-HN,es-NI,es-PA,es-PE,es-PR,es-PY,es-SV,es-VE,es-MX,es-US,eu,eu-ES,fi,fi-FI,fr,fr-FR,fr-CH,fr-BE,gl,gl-ES,gu,gu-IN,he,he-IL,iw,iw-IL,hu,hu-HU,hy,hy-AM,id,id-ID,is,is-IS,it,it-IT,it-CH,ja,ja-JP,jv,jv-ID,ka,ka-GE,km,km-KH,kn,kn-IN,ko,ko-KR,la,lo,lo-LA,lv,lv-LV,ml,ml-IN,mr,mr-IN,ms,ms-MY,nl,nl-NL,nb,nb-NO,ne,ne-NP,pl,pl-PL,pt,pt-BR,pt-PT,ro,ro-RO,ru,ru-RU,si-LK,sk,sk-SK,sr,sr-RS,su,su-ID,sv,sv-SE,sw,sw-TZ,sw-KE,ta,ta-IN,ta-SG,ta-LK,ta-MY,te,te-IN,tr,tr-TR,ur,ur-PK,ur-IN,yue,yue-HK,yue-Hant-HK,zh-HK,zh,zh-CN,zh-cmn,zh-cmn-CN,zh-Hans,zh-Hans-CN,zh-cmn-Hans,zh-cmn-Hans-CN,cmn-CN,cmn-Hans,cmn-Hans-CN,zh-TW,zh-Hant-TW,cmn-TW,cmn-Hant-TW,zh-cmn-TW,zh-cmn-Hant-TW,zu,zu-ZA\"\u003e\n\u003cdiv id=\"tw-ob\" class=\"tw-src-ltr\"\u003e\n\u003cdiv class=\"oSioSc\"\u003e\n\u003cdiv id=\"tw-target\"\u003e\n\u003cdiv id=\"kAz1tf\" class=\"g9WsWb PZPZlf\" data-attrid=\"tw-targetArea\" data-entityname=\"Google Translate\"\u003e\n\u003cdiv id=\"tw-target-text-container\" class=\"tw-ta-container F0azHf tw-nfl\" tabindex=\"0\"\u003e\n\u003chr data-start=\"2310\" data-end=\"2313\"\u003e\n\u003ch2 data-section-id=\"nz8vhe\" data-start=\"2315\" data-end=\"2324\"\u003e\u003ca title=\"Shop POLA at Tokyo Beauty Box | Worldwide Shipping\" href=\"https:\/\/tokyobeautybox.com\/collections\/pola\"\u003eShop More POLA →\u003c\/a\u003e\u003c\/h2\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"POLA","offers":[{"title":"Default Title","offer_id":54838396846398,"sku":null,"price":51.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0777\/9359\/1614\/files\/PolaWrinkleShotMedicalSerumDuoSingleSet15mL.jpg?v=1793804743","url":"https:\/\/tokyobeautybox.com\/zh\/products\/pola-wrinkle-shot-medical-serum-duo-single-set-15ml","provider":"Tokyo Beauty Box","version":"1.0","type":"link"}